While the industry has adopted different biosecurity practices and strategies to prevent, contain and isolate sites, specifically for the breeding herds, evidence suggests that wean-to-market sites play a role in maintaining and transmitting pathogens in swine populations. From the PRRS Symposium in Chicago, Gustavo Silva, Iowa State University, discusses the latest development in this Swine Health Information Center Wean-to-Harvest Biosecurity Research project.