Salt intake physiologically set

Salt intake physiologically set

Salt intake is controlled by networks in the brain and not by the salt in food.

A NEW study led by scientists affiliated with the University of California-Davis (UC-Davis) adds further credence to the notion that concern about the amount of salt people consume may be misplaced.

According to the university, the study documents in humans what neuroscientists have reported for some time: Animals' sodium intake is controlled by networks in the brain and not by the salt in one's food. The findings have important implications for future U.S. nutrition policy directed at sodium intake.

Findings from the new study, titled "Normal Range of Human Dietary Sodium Intake: A Perspective Based on 24-hour Urinary Sodium Excretion Worldwide," was published online Aug. 26 in advance of the print edition of the American Journal of Hypertension.

For decades, U.S. health policies have emphasized the importance of limiting salt consumption in order to lower the risks of cardiovascular disease related to high blood pressure. This new scientific review, however, found that people have a very predictable and narrow range of daily sodium intake — approximately 2,600-4,800 mg per day — that has remained quite constant during more than 50 years and across at least 45 countries, UC-Davis said.

"Our data clearly demonstrate that humans' sodium (salt) intake is regulated within a relatively narrow 'normal' range that is defined by the body's physiology and biological need rather than by the food supply," lead author David McCarron, a physician and adjunct professor in the UC-Davis department of nutrition, said. "The nation's future health policies and guidelines should be developed based on that biologically determined range."

He noted that these findings were recently presented to an Institute of Medicine committee, which prepared a report, "Sodium Intake in Populations — Assessment of Evidence."

Co-author Joel Geerling, a physician and neuroscientist at Harvard Medical School's Beth Israel Deaconess Hospital, said, "These findings are consistent with the idea that eating salt is physiologically controlled, as predicted by decades of efforts by the neuroscience community directed at understanding the brain's role in the regulation of sodium appetite."

The new study's combined data represent more than 69,000 research participants in 190 government-sponsored studies in 45 countries over the past five decades. Salt intake was measured in terms of sodium excreted in the urine during a 24-hour period. The average and range of the combined data were nearly identical to those first reported in the researchers' 2009 study on salt intake.

"This analysis defines the normal range and mean value for sodium intake in humans and documents that the range has not changed during five decades, nor has it been influenced by ethnicity or the unique dietary practices of various cultures around the world," McCarron said.

"If future nutritional guidelines are to be effective, they must be based on the scientific reality reflected in these data, which have documented that a normal range for human sodium intake exists," he said. "Sodium intake will not be changed by altering the salt content of food products or other public policy attempts to limit sodium consumption."


Volume:85 Issue:38

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