BIOMIN has received the first-ever European Food Safety Authority (EFSA) positive opinion for a purified enzyme capable of biotransforming fumonisins.
In its scientific opinion, EFSA concluded that BIOMIN's FUMzyme is safe not only for animals, humans and the environment, but also demonstrably efficacious in pigs. FUMzyme was originally isolated from the fumonisin-degrading soil bacteria Sphingopyxis sp. MTA 144 and identified as fumonisin esterase by the BIOMIN Research Center.
EFSA acknowledged the product's efficacy in degrading fumonisins to compounds of significantly lower toxicity in the gastrointestinal tract of animals.
EFSA concluded that FUMzyme has the capacity to biotransform fumonisins from contaminated pig feed at a minimum dose of 15 U/kg feed.
Until now, the binding of fumonisins to adsorptive substances was the only solution available to counter fumonisin intoxication. Due to the molecular structure of these mycotoxins and pH dependence of the reaction, fumonisins are only insufficiently adsorbed by mycotoxin-binding products in the gastrointestinal tract, BIOMIN said.
In 2013, BIOMIN became the first company to receive the European Commission authorization for feed additives with mycotoxin-counteracting properties.