Method has potential to predict AMR more efficiently and generate large amount of data for other epidemiological studies and analysis.

June 5, 2019

2 Min Read
Whole-genome sequencing may better target AMR
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The use of whole-genome sequencing can improve the way antimicrobial resistance (AMR) is monitored in food and animals, according to a new report from the European Food Safety Authority (EFSA).

Ahead of the revised European legislation on AMR monitoring that is due to come into force in 2021, EFSA suggested that these methods could gradually be introduced into member state monitoring activities.

Using whole-genome sequencing, experts can identify resistant genes in bacteria as opposed to current phenotypical methods that test bacteria for resistance to specific antibiotics, EFSA said in an announcement. This not only has the potential to predict AMR more efficiently but also generates a large amount of data that can be used for other epidemiological studies and analysis.

EFSA’s report additionally highlights the need to monitor AMR in seafood, about which little is known. This is linked to the recent expansion of aquaculture production and the increase in products imported into the European Union.

Experts emphasized the importance of understanding how AMR emerges and spreads in the environment where food is produced or processed — an area that requires more investigation and upon which EFSA will soon start working, the announcement said.

Additionally, the report gives recommendations on sample sizes and suggests monitoring resistance to antibiotics that have become relevant for public health and that are not currently monitored, EFSA said, which may allow better detection of possible new mechanisms of resistance. Monitoring is a critical component of the response to AMR and is one of the priorities of the EU action plan on AMR.

EFSA reviewed the way AMR monitoring is currently done in the EU, accounting for the latest scientific and technological developments.

The EFSA report is: "Scientific Report: Technical Specifications on Harmonised Monitoring of Antimicrobial Resistance in Zoonotic & Indicator Bacteria from Food-Producing Animals & Food."

Source: European Food Safety Authority, which is solely responsible for the information provided and is wholly owned by the source. Informa Business Media and all its subsidiaries are not responsible for any of the content contained in this information asset.

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