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Researchers assess efficacy of Salmonella in turkeys

DarcyMaulsby/iStock/Thinkstock turkeys in barn
Vaccination with BBS 866 or AviPro Megan Egg significantly reduced colonization by S. Reading in turkeys.

USPOULTRY and the USPOULTRY Foundation recently announced the completion of a funded research project at the USDA, ARS, National Disease Center in which researchers assessed the efficacy of Salmonella vaccines to reduce S. Reading colonization, dissemination and persistence in turkeys. The research was made possible in part by the Cooper Family Foundation and proceeds from the International Poultry Expo, part of International Production & Processing Expo (IPPE). The research is part of the association’s comprehensive research program encompassing all phases of poultry and egg production and processing.

The previous foodborne outbreak of Salmonella enterica serovar Reading revealed the need for effective control of this serovar in turkey production. Vaccination can reduce Salmonella in poultry. Dr. Shawn Bearson, a microbiologist within the Food Safety & Enteric Pathogens Research Unit at the USDA, ARS, National Animal Disease Center, recently completed a research project that assessed the vaccine efficacy of two live-attenuated Salmonella vaccines, the commercial AviPro Megan Egg vaccine and an internally developed cross-protective BBS 866 DIVA vaccine, to reduce S. Reading colonization in turkeys.

Two vaccination delivery methods were used for both vaccines: oral gavage for administration of primary and booster vaccinations as well as a vaccination regimen with a primary aerosol and water-delivered booster. Compared to non-vaccinated turkeys, all vaccinated groups had 10-1000 times less S. Reading in the cecal tonsils and cecal contents at 1-2 weeks after S. Reading challenge.

Findings showed that vaccination with BBS 866 or AviPro Megan Egg significantly reduced colonization by S. Reading in turkeys, indicating that these vaccines are cross-protective and could be a pre-harvest intervention strategy against this serovar.

The research summary can be found on the USPOULTRY website.

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