Zoetis has announced that its INFORCE 3 has earned a single nostril administration claim to make it more convenient to administer.

According to the company, protection against respiratory disease early in life with INFORCE 3 helps calves stay healthy, develop to their full genetic potential and reduce the risk of illness later in life.

Studies demonstrated that when the full 2-mL dose was administered into a single nostril in neonatal calves, INFORCE 3 protected against respiratory disease caused by infectious bovine rhinotracheitis (IBR) virus, bovine respiratory syncytial virus (BRSV) and parainfluenza 3 (PI₃) virus, Zoetis said.

In additional studies, INFORCE 3 also demonstrated the ability to override maternal antibodies to moderate IBR respiratory disease for at least 15 weeks and provided IBR respiratory protection for more than six months in IBR-naïve neonatal calves.

“INFORCE 3 delivers levels of protection and duration of immunity unmatched by any other intranasal vaccine,” said Dr. Nathan Voris, senior marketing manager with Zoetis. “Providing effective, long-lasting protection for the young calf is a big deal because illness during the calf’s first 60 days of life can set them back for their entire lifetime. Veterinarians and cattle producers utilize INFORCE 3 more than any other vaccine because they have observed the safe and effective respiratory protection it provides.”

Developed specifically for needle-free intranasal administration, INFORCE 3 from Zoetis was the first respiratory vaccine that prevents respiratory disease caused by BRSV while also aiding in the prevention of IBR and PI₃.

The vaccine contains proprietary temperature-sensitive IBR and PI₃ viral strains, as well as naturally temperature-sensitive BRSV. This formulation stimulates protective immunity in the nasal passages, where respiratory infections start, while also priming the immune system for a rapid memory response to subsequent vaccination or disease challenge. INFORCE 3 is safe for use in all types, ages and classes of calves, including neonatal calves and weaned and high-stress stocker calves.