Technique delves into bacterial resilience, antibiotic target

Variant of CRISPR technology paired with computerized imaging reveals essential gene networks in bacteria.

Researchers at the University of California-San Francisco (UCSF) and Stanford University have performed the first comprehensive survey of the central genes and proteins essential to bacterial life.

The study, which combined a new variant of CRISPR gene-editing technology with automated cell imaging, generated a new understanding of the fundamental gene networks that make bacteria so resilient to environmental stress and — increasingly — to antibacterial drugs.

The research a

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