Groundbreaking research from the University of Alberta has identified the structure of the infectious prion protein — the cause of bovine spongiform encephalopathy (BSE), chronic wasting disease in deer and elk and Creutzfeldt-Jakob disease in humans — which has long remained a mystery.
The infectious prion protein is a misfolded protein, which makes it very difficult to purify and study, the researchers said. Because it clumps together, standard structural biology techniques canno
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