Pathogen sequencing project maps first genomes

Pathogen sequencing project maps first genomes

STRIKING a blow at foodborne diseases, the 100K Pathogen Genome Project at the University of California-Davis announced that it has sequenced the genomes of its first 10 infectious microorganisms, including strains of salmonella and listeria.

"We are creating a free, online encyclopedia or reference database of genomes so that, during a foodborne disease outbreak, scientists and public health professionals can quickly identify the responsible microorganism and track its source in the food supply using automated information handling methods," professor Bart Weimer said.

Weimer is director of the 100K Genome Project and co-director of [email protected] Davis, the Sacramento, Cal., facility where the sequencing is carried out.

Weimer estimated that the availability of this genomic information will halve the time necessary to diagnose and treat foodborne illnesses and will enable scientists to make discoveries that can be used to develop new methods for controlling disease-causing microorganisms in the food chain.

The project is dedicated to sequencing the genomes of 100,000 bacteria and viruses that cause serious foodborne illnesses in people around the world.

The initial 10 genome sequences mark the first in a series that the project will enter into a publicly available database at the National Center for Biotechnology Information of the National Institutes of Health.

"This initial release validates the entire process, from start to finish, of acquiring the bacterium, producing the genome sequence and making automated public releases," Weimer said.

Weimer said the 100K Genome Project currently is sequencing a second set of 1,500 microbial genomes, with an anticipated release this fall.

Volume:85 Issue:22

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