Three modifications to vancomycin's structure (shown in blue) give it new mechanisms of action for fighting infection. (Credit: The Scripps Research Institute. Image courtesy Boger Lab.)
Three modifications to vancomycin's structure (shown in blue) give it new mechanisms of action for fighting infection.

New antibiotic packs punch against bacterial resistance

Discovery makes this version of vancomycin the first antibiotic to have three independent mechanisms of action.

Scientists at The Scripps Research Institute (TSRI) have given new superpowers to the antibiotic vancomycin — an advance that could eliminate the threat of antibiotic-resistant infections for years to come.

The researchers, led by Dale Boger, co-chair of the TSRI department of chemistry, discovered a way to structurally modify vancomycin to make an already-powerful version of the antibiotic even more potent.

"Doctors could use this modified form of vancomycin without fea

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