In the periplasm — the space between the inner and outer membranes of a bacteria's cell wall — defensive proteins that detect a poison assemble like barrel staves to form a tunnel between pumps in the cell's inner and outer membranes to eject the intruders. Artist's conception by Ace George Santiago, Cornell University.
In the periplasm — the space between the inner and outer membranes of a bacteria's cell wall — defensive proteins that detect a poison assemble like barrel staves to form a tunnel between pumps in the cell's inner and outer membranes to eject the intruders.

E. coli bacteria defense secret revealed

Findings could lead to ways to combat antibiotic-resistant bacteria with a "cocktail" of drugs.

By tagging a cell's proteins with fluorescent beacons, Cornell researchers have found out how Escherichia coli bacteria defend themselves against antibiotics and other poisons.

When undesirable molecules show up, the bacterial cell opens a tunnel though its cell wall and "effluxes" the intruders, i.e., pumps them out.

"Dynamic assembly of these tunnels has long been hypothesized," Cornell professor of chemistry and chemical biology Peng Chen said. "Now, we see them."<

All access premium subscription

This content requires a subscription to Feedstuffs in order to access. If you are a paid subscriber, use your email and password to Log In now.


Current Feedstuffs Subscribers: Online and mobile access are now included at no charge to you. To read this article, use your subscriber email and password to log-in to your account (or contact us for assistance in updating your account.)


Not Currently a Subscriber: Subscribe NOW to Feedstuffs and receive our print and/or digital publications, enewsletters and premium online content. Visit Feedstuffs.com and click on Subscribe at the top of the page for more information.


SUBSCRIBE NOW https://circulation.feedstuffs.com/Publications.aspx


TO RENEW YOUR SUBSCRIPTION https://circulation.feedstuffs.com/SubscriptionOffers.aspx


Hide comments

Comments

  • Allowed HTML tags: <em> <strong> <blockquote> <br> <p>

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Publish